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10,000 customer reviews.

4.7 Overall Satisfaction Rating based on over 10,000 Ratings from our customers.

Fall in Love with Lively South America

A South America cruise is an experience to behold. You’ll learn about the Nazca Lines in Peru and native Amazonians all while discovering amazing natural vistas and of course, sampling all the South American cuisine you can eat.

South America ports are usually included on expansive world cruises, but often booked as part of an Amazon and South American itinerary. No matter the length of your voyage, you’ll see incredible destinations and do amazing things. For instance, you could see Magellanic penguins nest near Punta Arenas, go sunbathing in Rio de Janeiro, dance until dawn in Argentina, or have a fun trip to Uruguay's largest winery.

As for landscapes, they vary wildly, from the lush Amazon rainforest to the dry Atacama Desert and Chilean fjords with towering glaciers. Fleets that offer South America voyages include Oceania, Holland America, Princess, Norwegian, Regent Seven Seas, Celebrity, Silversea, and Seabourn.

  • Destination Port 1 Departure Port
  • Destination port 2 Destination
SAUSTRLENDWLD
Exclusive "End of the World" Drive
$120

Experience rugged peaks, pristine lakes, ancient forests of the Andes, and the glacier-draped shores of the famed Beagle Channel.

SAMACHTPUNTOM
Exclusive Punta Tombo Penguins
$188

Visit the largest Magellan penguin colony in South America where you may walk among more than 500,000 penguins along a two-mile path.

SACACITYTOUR
Cartagena City Tour
$89

This fun adventure takes you around Cartagena for a close look at top attractions like Las Bovedas and Cartagena Bay. Entrance fees included.

SAVPCHJVALPOS
Valparaiso and Vina Del Mar (Pre Cruise)
$222

Enjoy a visit to a winery as well as the highlights of two beautiful coastal cities on this pre-cruise tour from Santiago to Valparaiso.

sababbhcbiket
Best of Buenos Aires Bike Tour
$80

On this bike tour of Buenos Aires's most fascinating places, you will experience the culture and history this city has to offer.

sastcjsjnlandhd
Half Day Los Andes to Valle Nevado...
$124

Get ready for spectacular views of the Andes on this Chile tour that takes you to two of the mountain range's most popular ski resorts.

 

Monthly Weather Averages

South America temperature graph
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South America rain graph
  • Temperature in Fahrenheit
  • Rain in Inches

Current Weather

Buenos Aires
90°F
Rain
Weather icon
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Friday

93° 72°
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Saturday

82° 69°
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Sunday

94° 72°
clear

Monday

83° 67°

357 CRUISES

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12 NIGHT SOUTH AMERICA Cruise

Departing From: Rio De Janeiro

Duration: 12 nights

Ship: MSC Preziosa (Ship Info)

Port of Call: Rio De Janeiro Brazil, Buzios Brazil, , Salvador Brazil, Maceio Brazil, , , , , , , Santa Cruz De Tenerife (canary Is) Spain, Funchal (madeira Is) Portugal (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

13625379821351032

From

$289

as little as $24.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
$289

USD

$539

USD

$749

USD

$1,479

USD

Voyager club DO YOU HAVE A FUTURE CRUISE CREDIT?

Redeem your future cruise credit with CruiseDirect. Speak to an Advisor today 1-888-407-2784

itinerary-image

3 NIGHT SOUTH AMERICA Cruise

Departing From: Santos

Duration: 3 nights

Ship: MSC Preziosa (Ship Info)

Port of Call: Santos (sao Paolo), Brazil, , Buzios, Brazil, Santos (sao Paolo), Brazil (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

13619809821351032

From

$289

as little as $96.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
$359

USD

$429

USD

$579

USD

$929

USD

  • Cruise Promotion
$289

USD

$399

USD

$499

USD

$849

USD

  • Cruise Promotion
$339

USD

$409

USD

$519

USD

$879

USD

Voyager club BEST PRICE GUARANTEE!

If you find a lower price online, we’ll match it!  

itinerary-image

13 NIGHT SOUTH AMERICA Cruise

Departing From: Santos

Duration: 13 nights

Ship: MSC Fantasia (Ship Info)

Port of Call: Santos (sao Paolo) Brazil, Rio De Janeiro Brazil, , , Maceio Brazil, , , , , , Santa Cruz De La Palma Spain, Funchal (madeira Is) Portugal, , Lisbon (cascais) Portugal (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1339428982118332

From

$299

as little as $23.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
$299

USD

$389

USD

$549

USD

$1,489

USD

Voyager club MAKE THE WORLD GREENER

CruiseDirect and One Tree Planted are planting a tree for every passenger who sails with us.

3 NIGHT SOUTH AMERICA Cruise

Departing From: Itajai

Duration: 3 nights

Ship: MSC Armonia (Ship Info)

Port of Call: Itajai (balneario Camboriu), Brazil, , Punta Del Este, Uruguay, Buenos Aires, Argentina (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1327312982110432

From

$299

as little as $100.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
$299

USD

$339

USD

- -

Voyager club FREE HOLDS

Lock in a great price, figure out your plans & pay later. Free Holds are available on the final step.

3 NIGHT SOUTH AMERICA Cruise

Departing From: Rio De Janeiro

Duration: 3 nights

Ship: MSC Armonia (Ship Info)

Port of Call: Rio De Janeiro, Brazil, Ilha Grande, Brazil, Ilhabela, Brazil, Itajai (balneario Camboriu), Brazil (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1327307982110432

From

$309

as little as $103.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
$309

USD

- - $519

USD

Voyager club DO YOU HAVE A FUTURE CRUISE CREDIT?

Redeem your future cruise credit with CruiseDirect. Speak to an Advisor today 1-888-407-2784