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10,000 customer reviews.

4.7 Overall Satisfaction Rating based on over 10,000 Ratings from our customers.

Fall in Love with Lively South America

A South America cruise is an experience to behold. You’ll learn about the Nazca Lines in Peru and native Amazonians all while discovering amazing natural vistas and of course, sampling all the South American cuisine you can eat.

South America ports are usually included on expansive world cruises, but often booked as part of an Amazon and South American itinerary. No matter the length of your voyage, you’ll see incredible destinations and do amazing things. For instance, you could see Magellanic penguins nest near Punta Arenas, go sunbathing in Rio de Janeiro, dance until dawn in Argentina, or have a fun trip to Uruguay's largest winery.

As for landscapes, they vary wildly, from the lush Amazon rainforest to the dry Atacama Desert and Chilean fjords with towering glaciers. Fleets that offer South America voyages include Oceania, Holland America, Princess, Norwegian, Regent Seven Seas, Celebrity, Silversea, and Seabourn.

  • Destination Port 1 Departure Port
  • Destination port 2 Destination
SAUSTRLENDWLD
Exclusive "End of the World" Drive
$120

Experience rugged peaks, pristine lakes, ancient forests of the Andes, and the glacier-draped shores of the famed Beagle Channel.

SAMACHTPUNTOM
Exclusive Punta Tombo Penguins
$188

Visit the largest Magellan penguin colony in South America where you may walk among more than 500,000 penguins along a two-mile path.

SACACITYTOUR
Cartagena City Tour
$89

This fun adventure takes you around Cartagena for a close look at top attractions like Las Bovedas and Cartagena Bay. Entrance fees included.

SAVPCHJVALPOS
Valparaiso and Vina Del Mar (Pre Cruise)
$222

Enjoy a visit to a winery as well as the highlights of two beautiful coastal cities on this pre-cruise tour from Santiago to Valparaiso.

sababbhcbiket
Best of Buenos Aires Bike Tour
$80

On this bike tour of Buenos Aires's most fascinating places, you will experience the culture and history this city has to offer.

sastcjsjnlandhd
Half Day Los Andes to Valle Nevado...
$124

Get ready for spectacular views of the Andes on this Chile tour that takes you to two of the mountain range's most popular ski resorts.

 

Monthly Weather Averages

South America temperature graph
month graph
South America rain graph
  • Temperature in Fahrenheit
  • Rain in Inches

Current Weather

Buenos Aires
62°F
Rain
Weather icon
chancerain

Tuesday

64° 56°
chancerain

Wednesday

65° 54°
clear

Thursday

72° 53°
chancerain

Friday

69° 56°

280 CRUISES

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280 Cruises

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3 NIGHT SOUTH AMERICA Cruise

Departing From: Santos

Duration: 3 nights

Ship: MSC Armonia (Ship Info)

Port of Call: Santos (sao Paolo), Brazil, Buzios, Brazil, , Santos (sao Paolo), Brazil (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1382865982110432

From

$289

as little as $96.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
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$309

USD

$359

USD

$459

USD

$639

USD

  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$289

USD

$349

USD

$439

USD

$619

USD

Voyager club BEST PRICE GUARANTEE!

If you find a lower price online, we’ll match it!  

3 NIGHT SOUTH AMERICA Cruise

Departing From: Santos

Duration: 3 nights

Ship: MSC Armonia (Ship Info)

Port of Call: Santos (sao Paolo), Brazil, Balneario Camboriu, Brazil, , Santos (sao Paolo), Brazil (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1382876982110432

From

$299

as little as $100.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$329

USD

$369

USD

$459

USD

$639

USD

  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$299

USD

$369

USD

$459

USD

$639

USD

Voyager club FREE HOLDS

Lock in a great price, figure out your plans & pay later. Free Holds are available on the final step.

4 NIGHT SOUTH AMERICA Cruise

Departing From: Santos

Duration: 4 nights

Ship: MSC Preziosa (Ship Info)

Port of Call: Santos (sao Paolo), Brazil, Ilha Grande, Brazil, Buzios, Brazil, , Santos (sao Paolo), Brazil (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

13829599821351032

From

$299

as little as $75.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$299

USD

$399

USD

$489

USD

$749

USD

Voyager club MAKE THE WORLD GREENER

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4 NIGHT SOUTH AMERICA Cruise

Departing From: Santos

Duration: 4 nights

Ship: MSC Preziosa (Ship Info)

Port of Call: Santos (sao Paolo), Brazil, Balneario Camboriu, Brazil, Porto Belo, Brazil, , Santos (sao Paolo), Brazil (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

13829429821351032

From

$299

as little as $75.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$299

USD

$399

USD

$489

USD

$749

USD

Voyager club BOOK NOW, PAY LATER

Payment plans with no late fees or surprises when booking with Uplift

4 NIGHT SOUTH AMERICA Cruise

Departing From: Santos

Duration: 4 nights

Ship: MSC Preziosa (Ship Info)

Port of Call: Santos (sao Paolo), Brazil, Porto Belo, Brazil, Balneario Camboriu, Brazil, , Santos (sao Paolo), Brazil (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

13827979821351032

From

$299

as little as $75.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$299

USD

$389

USD

$479

USD

$739

USD

  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$309

USD

$399

USD

$479

USD

$739

USD

  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$299

USD

$399

USD

$489

USD

$749

USD

  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$339

USD

$439

USD

$529

USD

$789

USD

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