MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.
26 CRUISES
26 Cruises
7 NIGHT SOUTH AMERICA Cruise
Departing From: Santos
Duration: 7 nights
Ship: MSC Preziosa (Ship Info)
Port of Call: Santos (sao Paolo), Brazil, , Punta Del Este, Uruguay, Buenos Aires, Argentina, Buenos Aires, Argentina, Montevideo, Uruguay, , Santos (sao Paolo), Brazil (Itinerary Details)
Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding
Bonus Details
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4 NIGHT SOUTH AMERICA Cruise
Departing From: Santos
Duration: 4 nights
Ship: MSC Preziosa (Ship Info)
Port of Call: Santos (sao Paolo), Brazil, Porto Belo, Brazil, Balneario Camboriu, Brazil, , Santos (sao Paolo), Brazil (Itinerary Details)
Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

From
$829
as little as $207.00/night
MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.
Bonus Details
BEST PRICE GUARANTEE!
If you find a lower price online, we’ll match it!
4 NIGHT SOUTH AMERICA Cruise
Departing From: Santos
Duration: 4 nights
Ship: MSC Fantasia (Ship Info)
Port of Call: Santos (sao Paolo), Brazil, Buzios, Brazil, Ilha Grande, Brazil, , Santos (sao Paolo), Brazil (Itinerary Details)
Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

From
$929
as little as $232.00/night
MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.
Bonus Details
MAKE THE WORLD GREENER
CruiseDirect and One Tree Planted are planting a tree for every passenger who sails with us.
8 NIGHT SOUTH AMERICA Cruise
Departing From: Buenos Aires
Duration: 8 nights
Ship: MSC Musica (Ship Info)
Port of Call: Buenos Aires, Argentina, , , Rio De Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, , Montevideo, Uruguay, Buenos Aires, Argentina (Itinerary Details)
Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

From
$960
as little as $120.00/night
MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.
Departure Date | Bonus | Interior | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
$960 USD |
$1,510 USD |
$2,600 USD |
$4,900 USD |
|||
$960 USD |
$1,510 USD |
$2,210 USD |
$4,900 USD |
|||
$960 USD |
$1,510 USD |
$2,210 USD |
$4,900 USD |
Bonus Details
FREE HOLDS
Lock in a great price, figure out your plans & pay later. Free Holds are available on the final step.
8 NIGHT SOUTH AMERICA Cruise
Departing From: Montevideo
Duration: 8 nights
Ship: MSC Musica (Ship Info)
Port of Call: Montevideo, Uruguay, Buenos Aires, Argentina, , , Rio De Janeiro, Brazil, Buzios, Brazil, Ilhabela, Brazil, , Montevideo, Uruguay (Itinerary Details)
Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

From
$960
as little as $120.00/night
MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.
Departure Date | Bonus | Interior | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
$1,190 USD |
$1,570 USD |
$2,310 USD |
- | |||
$960 USD |
$1,510 USD |
$2,210 USD |
- | |||
$960 USD |
$1,510 USD |
$2,210 USD |
- |