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Book Cruises Leaving from Rome, Italy Online

If Rome isn't on your travel bucket list, you've either already been or simply forgotten to add it. It was the center of the Roman Empire and one of the biggest hubs during the Renaissance. Italy's capital is full of endless historic sites. Highlights include the Vatican Museums, the Roman Forum, the Colosseum, the Pantheon, and St. Peter's Basilica. Seeing Michelangelo's Sistine Chapel frescoes alone would make your trip worth it!

Of course, if history, art, and architecture aren't really your cup of cappuccino, you're still likely to love Rome. The culinary scene is world-class here. The vibrant nightlife is also not to be missed if you love live music and dance clubs. Book a last minute cruise from Rome and discover why they call it the Eternal City before you set sail!

  • Airport
  • Departure Port

Hotel In Rome

La Casa Degli Elfi Hotel Image
La Casa Degli Elfi

Amazing Apartment In Ladispoli rm With 1 Bedrooms And Wifi Hotel Image
Amazing Apartment In Ladispoli rm With 1 Bedrooms And Wifi

Podere 1248 Hotel Image
Podere 1248

B&B A Piazza del Gesù Hotel Image
B&B A Piazza del Gesù

Flights To Rome

Monthly Weather Averages

Rome temperature graph
Rome month graph
Rome rain graph
  • Temperature in Fahrenheit
  • Rain in Inches

Current Weather

Rome
58°F
Rain
chancerain

Saturday

58° 47°
mostlycloudy

Sunday

60° 45°
chancerain

Monday

58° 44°
chancerain

Tuesday

65° 51°

258 CRUISES

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3 NIGHT WESTERN MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 3 nights

Ship: MSC Musica (Ship Info)

Port of Call: Civitavecchia (rome), Italy, Genoa (portofino), Italy, Cannes (c�te D Azur), France, Barcelona, Spain (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1481371982110818

From

$229

as little as $76.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
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$229

USD

$289

USD

$409

USD

$749

USD

Voyager club BEST PRICE GUARANTEE!

If you find a lower price online, we’ll match it!  

3 NIGHT EASTERN MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 3 nights

Ship: MSC Divina (Ship Info)

Port of Call: Civitavecchia (rome), Italy, , Mykonos, Greece, Izmir (ephesus), Turkey (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

14609039821349616

From

$269

as little as $90.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
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- $269

USD

$349

USD

$1,059

USD

Voyager club FREE HOLDS

Lock in a great price, figure out your plans & pay later. Free Holds are available on the final step.

7 NIGHT WESTERN MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 7 nights

Ship: MSC Lirica (Ship Info)

Port of Call: Civitavecchia (rome), Italy, Livorno (florence), Italy, Marseille (provence), France, Palma De Mallorca (baleari Is.), Spain, Valencia, Spain, , Cagliari (sardinia), Italy, Civitavecchia (rome), Italy (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1476841982110518

From

$279

as little as $40.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
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$339

USD

$449

USD

$829

USD

$1,159

USD

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$279

USD

$449

USD

$829

USD

$1,159

USD

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$279

USD

$449

USD

$829

USD

$1,159

USD

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$329

USD

$499

USD

$879

USD

$1,209

USD

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$879

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$1,049

USD

$1,429

USD

$1,759

USD

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$1,029

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$1,199

USD

$1,579

USD

$1,909

USD

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$739

USD

$599

USD

$979

USD

$1,309

USD

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$329

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$499

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$879

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$1,209

USD

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$329

USD

$499

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$879

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$1,209

USD

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$329

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$499

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$879

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$1,209

USD

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$379

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$549

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$929

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$1,259

USD

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$379

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$549

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$929

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$1,259

USD

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$439

USD

$549

USD

$989

USD

$1,259

USD

Voyager club MAKE THE WORLD GREENER

CruiseDirect and One Tree Planted are planting a tree for every passenger who sails with us.

6 NIGHT WESTERN MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 6 nights

Ship: MSC Musica (Ship Info)

Port of Call: Civitavecchia (rome), Italy, Genoa (portofino), Italy, Cannes (c�te D Azur), France, Barcelona, Spain, Ibiza (baleari Is.), Spain, , Cagliari (sardinia), Italy (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1481372982110818

From

$349

as little as $58.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
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  • Cruise Promotion
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$349

USD

$469

USD

$659

USD

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