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Book Cruises Leaving from Rome, Italy Online

If Rome isn't on your travel bucket list, you've either already been or simply forgotten to add it. It was the center of the Roman Empire and one of the biggest hubs during the Renaissance. Italy's capital is full of endless historic sites. Highlights include the Vatican Museums, the Roman Forum, the Colosseum, the Pantheon, and St. Peter's Basilica. Seeing Michelangelo's Sistine Chapel frescoes alone would make your trip worth it!

Of course, if history, art, and architecture aren't really your cup of cappuccino, you're still likely to love Rome. The culinary scene is world-class here. The vibrant nightlife is also not to be missed if you love live music and dance clubs. Book a last minute cruise from Rome and discover why they call it the Eternal City before you set sail!

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Hotel In Rome

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Hotel San Giorgio

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Grand Hotel Helios

Amazing apartment in Ladispoli RM with 1 Bedrooms and WiFi Hotel Image
Amazing apartment in Ladispoli RM with 1 Bedrooms and WiFi

Flights To Rome

Monthly Weather Averages

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Rome
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Wednesday

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Thursday

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Friday

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Saturday

66° 51°

226 CRUISES

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6 NIGHT WESTERN MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 6 nights

Ship: MSC Grandiosa (Ship Info)

Port of Call: Civitavecchia (rome), Italy, Palermo (monreale), Italy, Valletta, Malta, , Barcelona, Spain, Marseille (provence), France, Genoa (portofino), Italy (Itinerary Details)

Best For: Family with Teens, Gourmet, Honeymoon, Romantic, Senior

13924559821409118

From

$279

as little as $47.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
$279

USD

- $569

USD

$2,249

USD

Voyager club DO YOU HAVE A FUTURE CRUISE CREDIT?

Redeem your future cruise credit with CruiseDirect. Speak to an Advisor today 1-888-407-2784

6 NIGHT MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 6 nights

Ship: MSC Poesia (Ship Info)

Port of Call: Civitavecchia (rome), Italy, Genoa (portofino), Italy, Marseille (provence), France, Barcelona, Spain, , Civitavecchia (rome), Italy, Genoa (portofino), Italy (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1355095982118175

From

$329

as little as $55.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$329

USD

$469

USD

$569

USD

$1,259

USD

Voyager club BEST PRICE GUARANTEE!

If you find a lower price online, we’ll match it!  

7 NIGHT WESTERN MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 7 nights

Ship: MSC Seashore (Ship Info)

Port of Call: Civitavecchia (rome), Italy, Palermo (monreale), Italy, , Ibiza (baleari Is.), Spain, Valencia, Spain, Marseille (provence), France, Genoa (portofino), Italy, Civitavecchia (rome), Italy (Itinerary Details)

Best For: No Style Attached.

13324579821453818

From

$349

as little as $50.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
$409

USD

- $849

USD

$1,449

USD

  • Cruise Promotion
  • Cruise Promotion
- - $1,039

USD

$1,339

USD

  • Cruise Promotion
  • Cruise Promotion
- - $939

USD

$1,319

USD

  • Cruise Promotion
  • Cruise Promotion
- - $859

USD

$1,319

USD

  • Cruise Promotion
  • Cruise Promotion
$349

USD

$539

USD

$709

USD

$1,169

USD

  • Cruise Promotion
  • Cruise Promotion
$509

USD

$699

USD

$869

USD

$1,329

USD

  • Cruise Promotion
  • Cruise Promotion
$569

USD

$759

USD

$929

USD

$1,389

USD

  • Cruise Promotion
  • Cruise Promotion
- - $1,019

USD

$1,439

USD

  • Cruise Promotion
  • Cruise Promotion
$699

USD

- $1,009

USD

$1,579

USD

  • Cruise Promotion
  • Cruise Promotion
$709

USD

$909

USD

$1,169

USD

$1,609

USD

  • Cruise Promotion
  • Cruise Promotion
$649

USD

$839

USD

$1,229

USD

$1,689

USD

  • Cruise Promotion
  • Cruise Promotion
$809

USD

$999

USD

$1,429

USD

$1,959

USD

  • Cruise Promotion
  • Cruise Promotion
$909

USD

- $1,319

USD

$1,739

USD

  • Cruise Promotion
  • Cruise Promotion
$799

USD

$1,049

USD

$1,309

USD

$1,729

USD

  • Cruise Promotion
  • Cruise Promotion
$1,119

USD

- $1,469

USD

$1,889

USD

  • Cruise Promotion
  • Cruise Promotion
$1,059

USD

- $1,409

USD

$1,829

USD

  • Cruise Promotion
  • Cruise Promotion
- - $1,559

USD

$1,899

USD

  • Cruise Promotion
  • Cruise Promotion
- - - $2,419

USD

  • Cruise Promotion
  • Cruise Promotion
- - $1,519

USD

$1,939

USD

  • Cruise Promotion
  • Cruise Promotion
$899

USD

- $1,479

USD

$1,939

USD

  • Cruise Promotion
  • Cruise Promotion
$899

USD

- $1,359

USD

$1,779

USD

  • Cruise Promotion
  • Cruise Promotion
$799

USD

$1,049

USD

$1,239

USD

$1,619

USD

  • Cruise Promotion
  • Cruise Promotion
$839

USD

- $1,249

USD

$1,629

USD

  • Cruise Promotion
  • Cruise Promotion
$919

USD

$1,109

USD

$1,279

USD

$1,739

USD

  • Cruise Promotion
  • Cruise Promotion
$699

USD

$839

USD

$1,049

USD

$1,469

USD

  • Cruise Promotion
  • Cruise Promotion
$599

USD

$789

USD

$959

USD

$1,419

USD

  • Cruise Promotion
  • Cruise Promotion
$659

USD

$849

USD

$1,019

USD

$1,479

USD

Voyager club MAKE THE WORLD GREENER

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5 NIGHT MEDITERRANEAN Cruise

Departing From: Civitavecchia (Rome)

Duration: 5 nights

Ship: MSC Poesia (Ship Info)

Port of Call: Civitavecchia (rome), Italy, Genoa (portofino), Italy, Marseille (provence), France, Barcelona, Spain, , Civitavecchia (rome), Italy (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1389033982118175

From

$359

as little as $72.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
  • Cruise Promotion
$359

USD

$479

USD

$609

USD

$1,179

USD

Voyager club FREE HOLDS

Lock in a great price, figure out your plans & pay later. Free Holds are available on the final step.

8 NIGHT MIDDLE EAST Cruise

Departing From: Civitavecchia (Rome)

Duration: 8 nights

Ship: MSC Orchestra (Ship Info)

Port of Call: Civitavecchia (rome), Italy, , Katakolon (olympia), Greece, Heraklion (crete), Greece, Suez Canal North, Egypt, Suez Canal South, Egypt, Aqaba (petra), Jordan, Sharm El-sheikh, Egypt, Safaga, Egypt (Itinerary Details)

Best For: Family with Kids, Family with Teens, Honeymoon, Romantic, Senior, Wedding

1383298982111031

From

$369

as little as $46.00/night

What's Included?

SAIL SAFE

MSC's Health & Safety Protocols allow you and your loved ones to cruise with the ultimate safety.

Learn More

Departure Date Bonus Interior Oceanview Balcony Suite
  • Cruise Promotion
  • Cruise Promotion
- $369

USD

$469

USD

-

Voyager club DO YOU HAVE A FUTURE CRUISE CREDIT?

Redeem your future cruise credit with CruiseDirect. Speak to an Advisor today 1-888-407-2784

Where Do Cruise Ships Leave From in Rome?

The Rome Cruise Terminal is actually located in Civitavecchia. Civitavecchia is about a 50-minute drive from the Fiumicino airport. It's also possible to take a train to Civitavecchia and then either walk or take a local bus to the port.

Where Can You Go on a Mediterranean Cruise From Rome?

Cruises departing from Rome call at ports including:

  • Palma de Mallorca
  • Barcelona
  • Naples
  • Cannes
  • Marseilles
  • Genoa
  • Florence
  • Valencia
  • Dubrovnik
  • Zadar

Many companies offer cruises departing from Rome with Mediterranean itineraries. Options include:

  • Azamara Club Cruises
  • Crystal Cruises
  • Costa
  • Disney Cruise Line
  • Regent Seven Seas
  • Seabourn Cruise Line
  • Silversea Cruises
  • Viking Ocean Cruises

Are There Cruises From Rome to Greece?

Yes! Cruises leaving from Rome offer many choices for travelers seeking to visit Greece.

Cruise Line Port of Call Cruise Package

Celebrity Cruises

Argostoli

7 Night Eastern Mediterranean Cruise

MSC Cruises

Corfu, Katakolon, Heraklion, Piraeus

11 Night Western Mediterranean Cruise

Norwegian Cruise Line

Santorini Island, Mykonos, Piraeus, Chania

10 Night Eastern Mediterranean Cruise

Norwegian Cruise Line

Santorini Island, Piraeus, Mykonos, Rhodes, Chania

11 Night Eastern Mediterranean Cruise

Royal Caribbean International

Chania, Mykonos, Rhodes, Santorini, Athens

9 Night Eastern Mediterranean Cruise

Norwegian Cruise Line

Piraeus, Rhodes, Iraklion

13 Night Eastern Mediterranean Cruise

MSC Cruises

Corfu, Katakolon, Heraklion, Piraeus

11 Night Western Mediterranean Cruise

When Can You Find Cruises From Rome?

Since the city is in a popular and temperate region, a Rome cruise is a great vacation option for any season. Here are a few of our favorite itineraries in spring, summer, fall, and winter.

Rome Cruises in December Through February

Month Cruise Line Nights Ports of Call

December

Costa

7

La Spezia, Savona, Marseille, Barcelona, Palma de Mallorca

December

MSC

10

Genoa, Marseille, Barcelona, Gibraltar, Lisbon, Cadiz, Malaga

January

Norwegian

13

Iraklion, Haifa, Limassol, Kusadasi, Naples

February

MSC

7

Palermo, Valletta, Barcelona, Marseille, Genoa

February

Norwegian

21

Piraeus, Rhodes, Haifa, Safaga, Aqaba, Muscat, Abu Dhabi, Dubai

Cruises Out of Rome in March, April, and May

Month Cruise Line Nights Ports of Call

March

Viking Ocean

14

Naples, Haifa, Jerusalem, Limassol, Rhodes, Athens

April

MSC

3

Marseille, Genoa

April

Azamara Club

8

Amalfi, Sorrento, Brindisi, Kotor, Trieste, Venice

May

Celebrity

11

Catania, Valletta, Santorini, Mykonos, Naples

May

Royal Caribbean

9

Messina, Valletta, Mykonos, Santorini, Athens, Naples

Summer Cruises in June, July, and August

Month Cruise Line Nights Ports of Call

June

Disney

8

Salerno, La Spezia, Villefranche, Marseilles, Barcelona

July

Princess

7

Salerno, Kotor, Corfu, Chania, Mykonos, Athens

July

Seabourn

7

Livorno, Portofino, Frejus, Bandol, Palamos, Palma de Mallorca, Barcelona

August

Royal Caribbean

3

Naples, Barcelona

August

Silversea

7

Naples, Lipari, Palermo, Cagliari, Alghero, Calvi, Monte Carlo

Cruises From Rome in September, October, and November

Month Cruise Line Nights Ports of Call

September

Princess

7

Salerno, Kotor, Corfu, Chania, Mykonos, Athens

September

Regent Seven Seas

8

Amalfi, Catania, Valletta, Nafplio, Santorini, Kusadasi, Athens

October

MSC

7

Cannes, Palma de Mallorca, Barcelona, Ajaccio, Genoa, La Spezia

October

Celebrity

14

Barcelona, Cartagena, Malaga, Tenerife, Miami

November

Costa

16

Savona, Marseille, Barcelona, Tenerife, Recife, Maceio, Salvador, Rio de Janeiro

Choose Your Cruise and Save

Whether you're dreaming of a three-day cruise from Rome to Barcelona or an extended journey to multiple continents, CruiseDirect can help you get there at the lowest prices. We also offer flexible payment plans for all of our cruises leaving from Rome, helping to bring them within reach for vacationers on a budget. And you'll never pay a booking fee when you book a Rome cruise with us: That's just one more way we work hard to help people make their dream vacations into reality. Book with us today and let us help you experience a once-in-a-lifetime getaway.